Aug 2026
Mapping the covalent cysteine interactome of Ebselen reveals high-sensitivity target engagement and redox proteome remodeling.
A chemical proteomic atlas of Ebselen-cysteine interactions is defined and provided a framework for understanding and optimizing covalent organoselenium therapeutics.
Yi-Ru Liu, Yu-Qiu Zi, Zhongyao Jiang et al.
· Bioorganic chemistry (Print) · 0 citations