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Yu-Shan Pan

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Open access Sep 2026

Epidemiology-guided discovery of a K1-specific lytic phage with therapeutic potential against ST23-K1 multidrug-resistant hypervirulent Klebsiella pneumoniae.

Phage therapy has emerged as a promising alternative for combating multidrug-resistant hypervirulent Klebsiella pneumoniae (MDR-hvKP) infections. Recent advances suggest that tailoring phage cocktails based on genomic surveillance of circulating strains might yield more effective regimens (Koncz et al., 2024). Here, we...

Hang Zhang, Yi-Fei Wei, Jia-Bao Xing et al. · 0 citations
Open access Oct 2026

Stepwise evolution of tigecycline resistance in Enterococcus hirae through early IS1216E-mediated tet(L) amplification and subsequent rpsJ mutations

Enterococcus spp. from food animals represent important reservoirs of antimicrobial resistance; however, the mechanisms underlying tigecycline resistance remain poorly understood. In this study, we investigated the genetic basis and evolutionary dynamics of tigecycline resistance in Enterococcus hirae. Among 118 Entero...

Yan-Bin Dong, Zhong-Yi Fang, Zheng-Yu Wei et al. · 0 citations

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