Open access
Sep 2026
The inflammatory UPR-IFNG axis reveals LBP as a survival and immunotherapy-response marker in hepatocellular carcinoma.
BACKGROUND Liver hepatocellular carcinoma (LIHC) remains difficult to stratify because tumor heterogeneity and an immunosuppressive microenvironment limit immune checkpoint blockade (ICB). The unfolded protein response (UPR) and interferon-gamma (IFNG) signaling connect cellular stress with tumor inflammation, but clin...
Nan Luo, Yu Tian
· Translational Oncology · 0 citations