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Author

Yu Tian

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Open access Sep 2026

Bacteroides cellulosilyticus-derived 2-hydroxyphenylacetic acid rectifies hepatic lipid homeostasis in MASLD by targeting the PPARγ-CD36 axis

The mechanism by which B. cellulosilyticus and 2HPAA alleviate MASLD by targeting the PPARγ-CD36 pathway is revealed, providing a new perspective for the study of gut microbiota-host interactions in regulating liver diseases.

Kaiwei Chen, Zizhen Yang, Ji-Xing Peng et al. · 0 citations
Open access Aug 2026

Complete genome-derived metabolic interactions reveal the impact of gut ecology on human health.

This work leverage 1,150 complete genomes to construct genome-scale metabolic models, demonstrating that draft assemblies introduce systematic artifacts and omit critical transport functions, and connects genome completeness with microbial ecological organization and provides a framework for linking metabolic interacti...

Yu-He Gu, Haoyu Wang, Jin-Long Yang et al. · 0 citations

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