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Yu-Tong Zhou

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Review Open access Sep 2026

Lactylation Remodels Tumorigenesis, Immune Microenvironment, and Therapeutic Response

Lysine lactylation (Kla) is a lactate-driven post-translational modification that covalently links lactyl groups to lysine residues, directly coupling cellular metabolic states to gene expression regulation and protein functional remodeling. Since its first report in 2019, extensive studies have confirmed that lactylat...

Yu-Fei Liu, Yu-Tong Zhou, Hui-Wen Xue et al. · 0 citations

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