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Yu-Wei Chen

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Open access Aug 2026

Genome mining guided identification of new furo[3,2-c]pyridones phaeopyridones A–C from the endophytic fungus Phaeobotryon negundinis 12020

Three pairs of new furo[3,2-c]pyridone derivative racemates, named (±)-phaeopyridones A–C (1–3), together with two new compounds, berkeleyamide E (4), and phaeopyranone (5), were isolated from the endophytic fungus Phaeobotryon negundinis 12020, along with three known compounds, (8S,9S)-dihydroisoflavipucine (6), (8S,9...

Ke Ye, Jie Shi, Hui-Min Wu et al. · 0 citations
Open access Aug 2026

TRACER navigates rearrangement-driven sesterterpene chemical space via multimodal enzyme-product representation learning

TRACER (terpene rearrangement annotation via co-attentive enzyme-product representation), a multimodal framework mapping the latent associations between sequence-derived enzyme representations and product chemotypes, establishes a predictive paradigm for the rational discovery and mechanistic elucidation of complex ter...

Cuiping Xing, Kangjie Lv, Wei-Yan Zhang et al. · 0 citations

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