Open access
Aug 2026
Behaviour of iPSC-Derived and Donor-Derived Hepatic Stellate Cells in Organoid Cultures Is Highly Variable and Contributes to Fibrotic Outcome
It is suggested that HSC heterogeneity, whether iPSC-derived or donor-derived, is an important factor in fibrotic output and response variability in human liver organoid models and should be considered in model design, interpretation and comparison between studies.
Yu-Wei Yang, Mina Kazemzadeh Dastjerd, Ayla J. Smout et al.
· Cells · 0 citations