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Author

Yu-Xiao Li

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Sep 2026

BRD2-Mediated TGR5 Destabilization Impairs Fatty Acid Oxidation and Drives Tubular Ferroptosis in Diabetic Kidney Injury.

A BRD2-TGR5-FAO signaling axis is delineated as a central pathogenic driver of tubular lipotoxicity and ferroptosis in diabetic kidney injury, and BRD2 inhibition is position as a mechanistically grounded therapeutic strategy for diabetic kidney disease.

Hui-Mei Zang, Fu-Cheng Zang, Hai-Yan Zhang et al. · 0 citations

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