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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Yu-Xin Hao

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Open access Sep 2026

A Myeloid-Specific Endogenous TRP1-CAR Knock-in Mouse Model for Melanoma-Targeted Immunotherapy

This myeloid-specific TRP1-CAR knock-in model shows in vitro antitumor activity and delayed melanoma progression in vivo, and provides a proof-of-concept framework for investigating antitumor activity and preliminary safety observations associated with sustained endogenous CAR expression.

Yu-Xin Hao, Xin Chen, Min Wang et al. · 0 citations

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