Review
Open access
Sep 2026
Chromatin remodeling in bone organoids: from epigenetic regulation to disease modeling and therapeutic translation
Chromatin remodeling contributes to skeletal development, tissue homeostasis, and disease by regulating nucleosome positioning, chromatin accessibility, and histone modifications. Bone organoids can partially reproduce the three-dimensional human bone microenvironment and provide new in vitro models for studying sk...
Yu-Xin Zheng, De-Feng Liu, Jun Hou et al.
· Frontiers in Genetics · 0 citations