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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Yu Xu

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2 papers indexed here

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Open access Sep 2026

Adipose-derived microRNA-518a drives hepatic cholesterol dysregulation and hypertension-related vascular remodeling in metabolic dysfunction-associated steatohepatitis via the MST1-AMPK-SREBP2 axis.

INTRODUCTION Metabolic dysfunction-associated steatohepatitis (MASH) is characterized by disrupted hepatic lipid homeostasis and progressive liver injury, and frequently coexists with hypertension and systemic vascular remodeling, suggesting shared pathophysiological mechanisms. Although adipose tissue-derived microRNA...

Yu Xu, Si-Han Zhang, Kun Wang et al. · 0 citations
Open access Sep 2026

Integrated multi-omics analyses identify an RAS-SLC11A2-associated molecular framework linking iron metabolism with PCOS-related cardiometabolic risk.

This study defines an RAS-SLC11A2 molecular framework linking iron metabolism dysregulation to PCOS-related cardiometabolic risk, elucidating the mechanisms connecting ovarian dysfunction, inflammation, oxidative stress and hypertension, and supports gentiopicroside as a promising therapeutic candidate.

Si-Han Zhang, Yu Xu, Tingting Cao et al. · 0 citations

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