Protein mutation effect generation asks a model to describe the functional consequence of a point mutation in natural language. Existing protein-to-text systems typically encode mutation information into undifferentiated representations, overlooking the organization of mutation-induced evidence across structural and bi...
Liuzhenghao Lv, Yu-Yang Liu, Yu-Yang Gao et al.· 0 citations
AI co-scientists could accelerate computational research, but over a long-running study the workflow also has to stay inspectable, resumable and reproducible, which requires persistent computational state and provenance. Here we present OpenAI4S, an open-source scientific research agent built around the principle of \e...
Gong-Bo Zhang, Hao Li, Yu Wang et al.· 0 citations
We introduce LabEvolver, a training-free framework that equips safe and grounded wet-lab agents with episodic memory from execution experience. LabEvolver couples a state-grounded inner trial loop for adaptive perception, online planning, and safety validation with an outer evolution loop that distills completed trajec...
Jingya Wang, Yuyang Gao, Liuzhenghao Lv et al.· 0 citations
HME is presented, a framework that combines multiple views of molecules to improve molecular understanding and design and enables bidirectional navigation of the chemical-linguistic space, achieving consistent improvements across molecular comprehension and design tasks over strong baselines.
Liuzhenghao Lv, Hao Li, Yu Wang et al.· Nature Communications· 0 citations
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