MitoQ in sepsis-associated acute lung injury: redox pharmacology, mechanistic evidence, and translational perspectives
Sepsis-associated acute lung injury (SALI) is characterised by mitochondrial oxidative stress, bioenergetic dysfunction, dysregulated inflammation, and disruption of the alveolar–capillary barrier. MitoQ is a mitochondria-targeted redox modulator with experimental evidence of mitochondrial and pulmonary protection, mak...