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Review Open access Sep 2026

Network-orchestrated regulation of thymic dysfunction and restoration

Thymic function is governed by an interconnected regulatory network spanning epithelial, stromal, immune and systemic dimensions. This network maintains thymic structure and function through coordinated regulation of epithelial homeostasis, stromal niche integrity, and systemic inputs. Disruption of this network contri...

Wen-Ai Sun, Hong-Bo Chen, Wei-Shan Guo et al. · 0 citations
Sep 2026

Oral-systemic metabolic crosstalk linking periodontal inflammation to energy homeostasis dysregulation.

The proposed PerioMet-HOMEOSTASIS framework provides a mechanistically interpretable understanding of oral-systemic metabolic interactions and supports early prediction and targeted intervention for metabolic disorders, aligning with the principles of integrative metabolism research.

Yu Zhang, Zhen Cai, Jing-Fei Zhang et al. · 0 citations

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