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Author

Yu Zhang

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Book Open access Aug 2026

ProtoPSR: Prototype-guided Pairwise Similarity Regularization for Robust Spatial Multi-Omics Integration

ProtoPSR is proposed, an unsupervised framework for robust spatial multi-omics domain discovery that stabilizes both local clustering structure and global pairwise relations and demonstrates strong robustness under modality-specific feature corruption.

Yu Zhang, Meng-Zhu Wang, Luoxi Jing et al. · 0 citations
Open access Jul 2026

scReGAT: Leveraging Knowledge of Regulatory Interactions to Predict Long-range Gene Regulation at Single-cell Resolution.

By integrating genome-wide association studies loci from Alzheimer's disease, multiple sclerosis, and schizophrenia, scReGAT identifies disease-associated cell types and uncovers candidate regulatory mechanisms underlying complex trait associations, positioning scReGAT as a robust and generalizable framework for decodi...

Baole Wen, Yanan Dang, Yu Zhang et al. · 0 citations

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