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Open access Sep 2026

Notoginsenoside R1 modulates the ATF4-CHOP-Bcl2 signaling pathway to alleviate mitochondrial stress damage and apoptosis in asthmatic airway epithelial cells

To investigate whether Notoginsenoside R1 (NG-R1) improves mitochondrial homeostasis by targeting the integrin signaling response (ISR) core transcription factor ATF4, thereby alleviating damage and apoptosis in asthma airway epithelial cells. House dust mites (HDM) were used to establish an in vivo asth...

Yao-Zheng Ling, Ling Guan, Yu Zhao et al. · 0 citations

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