Review
Open access
Sep 2026
Advances in CAR-T Cell Therapy: From Structural Design Innovations to Clinical Translation Challenges
A comprehensive overview of the core advancements in CAR-T technology is provided, emphasizing the evolution of the five generations of CAR structures, and the latest innovations in transfection techniques are explored, highlighting optimizations and comparative advantages of viral and non-viral vectors.
Hai-Xia Gao, Yuan Fang, Ping-Jing Zhang et al.
· Journal of Cancer · 0 citations