Integrative Network Toxicology Identifies NFKB1 and KIF11 as Candidate Genes Associated with 2-Hydroxyphenanthrene in the Context of Psoriasis
Background: 2-Hydroxyphenanthrene (2-PHE), a polycyclic aromatic hydrocarbon metabolite, has been implicated in immune and inflammatory dysregulation, yet its potential toxicological contribution to psoriasis remains unclear. This study aimed to identify candidate genes and pathways through which 2-PHE might influence...