Rational Engineering of Cellobiose Dehydrogenase via Substrate Pocket Redesign and Electron Transfer Optimization for Efficient Bioelectrosynthesis of Lactobionic Acid
Cellobiose dehydrogenase (CDH) is a fungal extracellular flavocytochrome crucial for biomass degradation and promising for bioelectrocatalytic applications. However, its practical application remains limited by suboptimal catalytic efficiency and inefficient electron transfer. Here, an integrated engineering strategy w...