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Oct 2026

CircENO1 drives gastric cancer progression via SPI1-mediated transcriptional activation of ENO1.

BACKGROUND Circular RNAs (circRNAs) are critical regulators of tumor biology. However, the role of circENO1 in gastric cancer (GC) remains unclear. This study investigated the biological function and molecular mechanism of circENO1 in GC. METHODS CircENO1 expression was evaluated using a publicly available dataset, c...

Yuan Yuan, Peng Zhang, Yu-Cheng Song · 0 citations
Open access Aug 2026

Prognostic signatures associated with immune and macrophage phenotypes in colorectal cancer: integrated single-cell and bulk transcriptomic analyses

Colorectal cancer (CRC) progression is closely associated with chronic inflammation and immune suppression mediated by M2 macrophages. This study systematically analyzed immune-related and macrophage polarization–related genes in CRC by integrating The Cancer Genome Atlas CRC dataset to identify differentially expr...

Yuan Yuan, Bing-Xi Zhou, Jin Liu et al. · 0 citations

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