Author

Yuan-Yuan Li

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Open access Sep 2026

SFTSV exploits PPM1K to inhibit apoptosis through the Bcl-2/BAX/Caspase-3 axis for efficient replication.

SFTSV (Severe fever with thrombocytopenia syndrome virus) causes severe febrile illness with high case fatality rates and poses a growing public health threat, while the molecular basis by which it subverts host survival pathways remains poorly understood. In this study, transcriptomic profiling identified PPM1K as a p...

Qian-Ruo Wang, Bao-Yan Wang, Peng-Hui Liu et al. · Virologica Sinica · 0 citations

Open access Sep 2026

RABV P protein activates the GSK3β-NF-κB signaling pathway to promote viral replication by interacting with the host protein Snapin

ABSTRACT Rabies virus (RABV), a lethal neurotropic pathogen, relies on interaction with the host to sustain neuronal infection; however, how it balances replication with neuronal survival remains unclear. Here, we revealed Snapin, a neuronal trafficking regulator, to be a critical host factor co-opted by RABV to enhanc...

Yu-Jie Bai, Yong-Sai Liu, Xiao-Yu Wu et al. · Journal of Virology · 0 citations