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Yuan-Yuan Wu

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Open access Sep 2026

LACTB2 Promotes the Growth and Migration of Non-Small Cell Lung Cancer By Regulating Mitochondrial Function.

Lung cancer remains one of the most commonly diagnosed cancers and the leading cause of cancer-related mortality worldwide. As a mitochondrial matrix protein, the role of β-lactamase-like protein 2 (LACTB2) is unclear in non-small cell lung cancer (NSCLC). In this study, we show that LACTB2 expression enhances the cell...

Jie Zhang, Qian Chen, Yuan-Yuan Wu et al. · 0 citations
Open access Sep 2026

SHP2 induced 125I radiotherapy-resistant in cervical cancer via modulating ERK/E2F1/SKP2 and P53/AMPK/FOXO signaling induced apoptosis and proliferation

To elucidate the molecular mechanismthrough which SHP2 confers resistance to 125I radiotherapy in cervical cancer by promoting the ERK/E2F1/SKP2 pathway while antagonizing the P53/AMPK/FOXO pathway. Bioinformatics analysis was employed to identify SHP2 associated genes.In vivo experiments assessed tumor progression v...

Hai-Ping Song, Jie Yang, Rong-Na Liu et al. · 0 citations

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