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Author

Yuchen Jiang

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Open access Aug 2026

NLRX1 contributes to immunotherapeutic resistance of head and neck squamous cell carcinoma by suppressing type I interferon pathway

Background Head and neck squamous cell carcinoma (HNSCC) faces challenges with limited immune checkpoint inhibitors (ICIs) efficacy. This study identifies NLRX1, highly expressed in HNSCC tumor cells, as a key driver of immune evasion and ICIs’ resistance. Methods This study investigated the role of NLRX1 in HNSCC immu...

Yu-Qi Wu, Yuchen Jiang, Dan Pan et al. · 0 citations

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