Author

Yue-Chao Sun

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Open access Aug 2026

Prophage landscapes in clinical MRSA: safety profiling and discovery of Lys81, a broad-spectrum bacteriolytic enzyme

A theoretical foundation for the clinical translation of MRSA prophages is established, positioning Lys81 as a novel candidate for treating drug-resistant bacterial infections.

Fang-Fei Ran, Ming-Lei Yang, Xiu-Xiu Zeng et al. · Frontiers in Microbiology · 0 citations

Open access Aug 2026

Broad-spectrum lytic potential of endolysins derived from prophages of clinical Salmonella isolates

Experimental evidence is provided supporting the development of prophage-derived endolysins as novel antimicrobial agents, and expressed the candidate endolysin Lys2823 and demonstrated its lytic activity against outer-membrane-permeabilized Salmonella.

Yuhui Liu, Xiu-Xiu Zeng, Hui Su et al. · Frontiers in Microbiology · 0 citations