Review
Open access
Oct 2026
Cellular senescence in ovarian cancer: a proposed geroncogenic shift linking aging, plasticity, and therapy resistance
Ovarian cancer develops within a biological environment that changes substantially with age. Beyond chronological aging, progressive alterations in genome maintenance, telomere integrity, epigenetic regulation, mitochondrial function, metabolism, inflammation, and immune surveillance can reshape the cellular and tissue...
Yu-Bo Zhang, Yue Han, Pin-Zhi Hou et al.
· Frontiers in Pharmacology · 0 citations