Genomic characterization of blaNDM-5- and mcr-1-positive Escherichia coli from retail chicken meat reveals distinct plasmid organizations
Carbapenems and polymyxins are critically important antimicrobial agents for treating severe infections caused by multidrug-resistant Gram-negative bacteria. The global dissemination of the carbapenem resistance gene blaNDM and colistin resistance gene mcr-1 threatens the effectiveness of these last-line antibiotics. F...