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Open access Oct 2026

An efficient and versatile reverse genetics system for bovine coronavirus facilitates antiviral evaluation

Bovine coronavirus (BCoV), a primary etiological agent of calf diarrhea, exhibits dual tropism for the respiratory and enteric tracts. However, research on BCoV gene function and pathogenesis has been limited by the lack of convenient and flexible reverse genetics tools. Herein, we report a robust reverse genetics syst...

Yi-Ran Zeng, Han-Qiong Gao, Yuan-Lu Lu et al. · 0 citations

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