Review
Open access
Sep 2026
Targeting innate immunity in cancer: mechanistic foundations, therapeutic vaccination, and clinical translation
Cancer evolves within tissue ecosystems in which innate immune surveillance and tumor-promoting inflammation jointly shape disease progression and therapeutic response. Innate receptors detect cellular stress, altered-self ligands, damaged-cell products and tumor-derived nucleic acids, thereby initiating cytotoxicity,...
Xing-Han Li, Yi-Tong Meng, Ji-Jun Dong et al.
· Frontiers in Immunology · 0 citations