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Open access Sep 2026

Polystyrene nanoplastics induce cardiotoxicity by driving myocardial metabolic reprogramming via the SDHA/Succinate/HIF-1α axis.

Micro- and nano-plastics (MNPs) have emerged as ubiquitous environmental contaminants and are increasingly implicated in adverse cardiovascular outcomes, yet their induced cardiotoxicity and potential mechanisms remain poorly understood. This study integrated in vivo mouse models, AC16 cardiomyocytes and a human cardia...

Tian-Yi Zhang, Y. Niu, Meng Chen et al. · 0 citations
Sep 2026

6PPD-Quinone Promotes Metabolic Dysfunction-Associated Steatotic Liver Disease through Immune-Inflammatory Disruption.

6PPD-quinone (6PPDQ), a transformation product of the tire antioxidant 6PPD, is widely detected in environmental and human matrices, yet its relevance to metabolic liver disease remains unclear. We examined its potential contribution to metabolic dysfunction-associated steatotic liver disease (MASLD) by integrating dis...

Xu-Lei Zuo, Li Ma, Xiao-Yu Hou et al. · 0 citations

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