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Author

Yue-Wen Tang

3 papers indexed here

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Open access Sep 2026

Celastrol in kidney diseases: From therapeutic duality and toxicity to precision renal targeting

Kidney disorders have become a prevalent global public health crisis, accompanied by soaring morbidity and insufficient therapeutic regimens in clinical practice. Celastrol, a biologically active pentacyclic triterpenoid isolated from Tripterygium wilfordii , is well documented to exert powerful anti-inflammatory,...

Yi-Ning Chen, Meng-Dan Lu, Ting Xu et al. · 0 citations
Open access Aug 2026

Exploring the anti-inflammatory targets of Gui-qi-yi-shen granules in diabetic nephropathy: insights from network pharmacology, transcriptomics, and experimental verification

Results indicate that GQYS treats DN mainly through the anti-inflammatory effects, providing a potential theoretical basis for its clinical application and demonstrating the reliability of the integrative strategy.

Jia-Wei Cao, Meng-Dan Lu, Peng Bi et al. · 0 citations
Review Open access Sep 2026

S100A8/A9 in Kidney Diseases: Mechanisms, Spatiotemporal Regulation, Biomarker Potential, and Therapeutic Implications

A spatiotemporal framework is proposed that extends beyond previous disease- or pathway-centered perspectives by integrating the timing and cellular context of S100A8/A9 signaling to establish stage-specific biomarker and therapeutic strategies targeting S100A8/A9 in precision nephrology.

Meng-Ge Zhu, Meng-Dan Lu, Jia-Wei Cao et al. · 0 citations

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