Kidney disorders have become a prevalent global public health crisis, accompanied by soaring morbidity and insufficient therapeutic regimens in clinical practice. Celastrol, a biologically active pentacyclic triterpenoid isolated from
Tripterygium wilfordii
, is well documented to exert powerful anti-inflammatory,...
Yi-Ning Chen, Meng-Dan Lu, Ting Xu et al.· Asian Pacific Journal of Tro...· 0 citations
Results indicate that GQYS treats DN mainly through the anti-inflammatory effects, providing a potential theoretical basis for its clinical application and demonstrating the reliability of the integrative strategy.
Jia-Wei Cao, Meng-Dan Lu, Peng Bi et al.· RSC Advances· 0 citations
A spatiotemporal framework is proposed that extends beyond previous disease- or pathway-centered perspectives by integrating the timing and cellular context of S100A8/A9 signaling to establish stage-specific biomarker and therapeutic strategies targeting S100A8/A9 in precision nephrology.
Meng-Ge Zhu, Meng-Dan Lu, Jia-Wei Cao et al.· Journal of Inflammation Rese...· 0 citations
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