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Review Open access Oct 2026

Complement–Metabolic Inflammation Crosstalk: Molecular Mechanisms and Therapeutic Targets in Type 2 Diabetes and Its Complications

Type 2 diabetes mellitus (T2DM), a global metabolic disease, is fundamentally characterized by a vicious cycle of chronic low-grade inflammation and metabolic dysregulation. The complement system, a key effector of innate immunity, has recently been recognized as deeply involved in initiating and amplifying metabolic i...

Yue Xie, Wen-Kun Ye, Xiao-Hua Wen et al. · 0 citations

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