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Open access Oct 2026

The Reversed Multi-Arm Two-Stage (RevMATS) Design in Oncology Dose Optimization.

The multi-arm two-stage (MATS) design combines proof-of-concept and dose optimization in a single study, which starts from parallel enrollments of participants across multiple cohorts (indications) at a dose selected from the dose-escalation study, which is usually the maximum tolerable dose (MTD) in traditional oncolo...

Yue Yang, Gu Mi, Ji Lin · 0 citations

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