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Yue-Yang Zhang

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Aug 2026

The DreAM-plus integrative RNA switch enhances transient AAV expression and reduces side effects of gene editing.

The uncontrolled long-term adeno-associated virus (AAV) expression prohibits therapeutic strategies that require more precise and dynamic regulation. For example, long-lasting expression of gene editors by AAV could augment off-target effects and immunogenicity. Drug-inducible RNA switches are desirable tools to achiev...

Yue-Yang Zhang, Yuhan Yang, Zhanzhao Liu et al. · 0 citations

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