EIF4A3-mediated downregulation of circ_0073586 promotes cadmium-induced lung carcinogenesis through SRSF9-triggered GPX4-dependent ferroptosis resistance.
Environmental heavy metal exposure represents a well-established etiological factor in pulmonary carcinogenesis. Although ferroptosis dysregulation contributes to Cadmium (Cd) induced pulmonary carcinogenesis, its precise molecular determinants remain elusive. Here, we demonstrated that Cd treatment (5 μM) induced EIF4...