Multi-Omics Integration and Proteomic Annotation Prioritize FAM174BAssociated Monocyte Remodeling in COPD and Lung Adenocarcinoma.
INTRODUCTION/BACKGROUND Chronic obstructive pulmonary disease (COPD) is associated with increased lung adenocarcinoma (LUAD) risk, but the cellular and molecular programs linking chronic inflammatory remodeling to malignancy remain incompletely defined. Transcriptomic overlap alone cannot distinguish potential upstream...