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Author

Yuki Nishimura

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Review Oct 2026

A hidden archaeal lineage with an ultra-reduced genome retaining only its replicative core.

Observations argue against a mutualistic mode of host dependence and reveal a second, distinct endpoint of cellular reduction: the informational core may represent the practical lower bound for a cell that retains the capacity to replicate and express its own genome.

Ryo Harada, Yuki Nishimura, Mami Nomura et al. · 0 citations
Open access Sep 2026

Functional unknomics of the SAR11 clade reveal hidden genetic potential underlying adaptation to bottom-up and top-down pressures

This study explored the function of the unknome of the SAR11 clade, the most abundant bacterial lineage in the ocean, with a particular focus on genes that provide insight into its ecology, and identified candidate viral defense systems within the unknome.

Satoshi Nishino, Kento Tominaga, Kimiho Omae et al. · 0 citations
Open access Aug 2026

SAR11 Genome Atlas: a genome and gene catalog for functional profiling of the most abundant bacterial clade in the ocean

The SAR11 Genome Atlas is presented, an interactive ortholog group (OG)-centered web resource that integrates 542 SAR11 genomes, including all 132 cultured strain genomes, with functional annotations, synteny, phylogenetic distribution, metatranscriptomic expression, and predicted protein structure information.

Satoshi Nishino, Kento Tominaga, Hajime Itoh et al. · 0 citations

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