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Yun-Fei Qi

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Open access Sep 2026

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

A genetically defined, multi‐hit mouse model that recapitulates the sustained hyperuricemia, metabolic dysregulation, and progressive fibrosis of human disease is established and glutathione peroxidase 3 (GPX3) is identified as a master regulator restraining precursor cell differentiation into Profib PT cells.

Yun-Fei Qi, Qiang Zhao, Lve Yue et al. · 0 citations

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