Yun-Feng Yu

Research trends and emerging topics in gut microbiota-derived metabolites and diabetic kidney disease: a multi-database bibliometric analysis (2014–2025)

Diabetic kidney disease (DKD) is a leading cause of end-stage renal disease. The gut-kidney axis has highlighted the potential involvement of gut microbial metabolites in the development and progression of DKD. This study aimed to systematically characterize the knowledge structure, research hotspots, collaboration...

Global research trends in enteric nervous system and gut microbiota: a bibliometric analysis (2005-2025)

Background The crosstalk between the enteric nervous system (ENS) and gut microbiota, along with their roles in disease, has garnered increasing scientific attention. However, a comprehensive and objective analysis of the field’s current status and evolutionary trajectory remains lacking. Methods We retrieved and scree...

PIEZO Channels in Metabolism and Metabolic Diseases: Research Advances and Therapeutic Strategies

Acute Lung Injury in the Context of Aging: Pathogenetic Mechanisms and Therapeutic Strategies.

The key mechanisms underlying aging-associated susceptibility to ALI are summarized and emerging therapeutic strategies targeting aging-related alterations are discussed, with emphasis on their translational challenges and clinical implications.

Single-Cell and Machine Learning Analyses Identify a PFKFB3-Centered Regulatory Network and Potential Salidroside Interaction in Coronary Heart Disease

The findings support PFKFB3 as a potential biomarker and mechanistic hub and suggest that salidroside may modulate its activity and provide a multi-layered framework connecting glycolytic remodeling, inflammatory transcriptional activity, and intercellular signaling in CHD.