Yun-Hai Pei

The active immune role of keratinocytes: from passive targets to key hubs in psoriatic inflammation

Psoriasis is a chronic immune-mediated inflammatory skin disease historically viewed as a disorder of keratinocyte hyperplasia, with subsequent recognition of central immune cell involvement. However, accumulating multi-omics and functional genomic evidence has reshaped this paradigm, positioning keratinocytes not mere...