Author

Yunjiang Li

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Open access Sep 2026

Sequential-Delivery Gel Microspheres Integrating HAase-Mediated ECM Remodeling and GA-Active Targeting for Deep Tumor Penetration in TACE-Treated HCC

Objective Transcatheter arterial chemoembolization (TACE) for hepatocellular carcinoma (HCC) is limited by inadequate intratumoral drug penetration. We developed a sequential-delivery composite gel microsphere system integrating hyaluronidase (HAase)-mediated microenvironment remodeling, glycyrrhetinic acid (GA)-mediat...

Xu-Wang Pan, Yun-Jiang Li, Yi-Dan Shao et al. · International Journal of Nan... · 0 citations

Open access Aug 2026

Dynamic prediction of HIV-related incomplete immune reconstitution: A multicenter, large cohort study using advanced joint modeling

A dynamic joint prediction system for IIR risk (DJPSIIR) using Bayesian joint modeling to analyze longitudinal data from 21,862 PLWH across 31 Chinese provinces (2003–2024) and demonstrated strong discriminatory performance with area under receiver operating characteristic curves.

Fang Liu, Han-Xi Zhang, Xi Wang et al. · Science Advances · 0 citations