Background/Objectives: Arenicolide A (ArA), a 26-membered macrolide from Micromonospora sp. GR10, is active against Mycobacterium tuberculosis, including multidrug-resistant strains. We developed and validated a liquid chromatography–tandem mass spectrometry (LC–MS/MS) method for ArA in rat plasma and applied it to pha...
Dahan Kim, Eun Kyung Shin, Seong-Wook Kang et al.· Pharmaceutics· 0 citations
This review critically evaluates marine-derived anti-flaviviral agents using two complementary dimensions, the infection stage implicated by experimental assays and the strength of evidence supporting that assignment, to help distinguish promising chemical candidate scaffolds from preliminary antiviral signals and guid...
Hyeonju Park, Min Seo Heo, Hyuk Nam Kwon et al.· Marine Drugs· 0 citations
Findings indicate how integrating genome mining, metabolomics, and molecular networking with targeted biosynthetic experiments can accelerate marine natural product discovery and unravel novel enzymatic functions and biosynthetic mechanisms in rare actinomycetes.
Ju-Wan Son, Hyeonju Park, Sang-He-On Jung et al.· Marine Drugs· 0 citations
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