ABSTRACT Sepsis remains a leading cause of mortality because current therapies fail to address its dynamically evolving pathophysiology, in which infection, oxidative stress, and immune dysfunction emerge sequentially and interdependently. Here, we present a pH‐adaptive nanozyme platform (MICP@HG) that orchestrates sta...
An-Lai Zou, Xiao-Xue Zhu, Run-Han Zhu et al.· Advancement of science· 0 citations
Abstract The human gut microbiome is increasingly viewed as an active regulator of host physiology, extending beyond earlier taxonomy‐centered descriptions of a complex microbial community. Accumulating evidence supports an organ‐like conceptual framework in which the gut microbiome exhibits spatially structured organi...
Yang Bi, Wei-Bin Song, Maria Glymenaki et al.· iMeta· 0 citations
A simple and robust strategy using dibenzocyclooctyne-mediated click chemistry to modulate CRISPR-Cas12a activity and shows that DBCO-modified activators can regulate CRISPR-Cas12a cleavage in three distinct states: maintain, enhance, and suppress.
