Yun-Shu Liu

From varied initiation strategies to converged ends: key factors in mRNA-LNPs formation and functional attributes.

The particle properties and transfection potency of mRNA lipid nanoparticles (mRNA-LNPs) are largely determined by the preparation process. We investigated the role of initiation methods by comparing distinct strategies, such as Conventional preparation method, Post-encapsulation method, and Tertiary butanol-water mono...