Author

Yun-Song Yu

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Open access Aug 2026

Host-dependent effects of mcr-1 and mcr-8 on fitness, virulence, and transmission in Escherichia coli and Klebsiella pneumoniae

Introduction As one of the most common groups of clinical pathogens, Enterobacterales pose a serious threat to global public health due to their multidrug-resistance. Polymyxin serves as a last-line treatment for infections caused by Carbapenem-resistant Enterobacterales (CRE). The emergence and spread of the mobilized...

Meng-Yu Zhou, Yi-Ning Ye, Nuo-You Cheng et al. · Frontiers in Microbiology · 0 citations

Open access Oct 2026

A wspA mutation in a clinical isolate of Pseudomonas aeruginosa results in rugose small colonies and enhances biofilm formation

ABSTRACT Pseudomonas aeruginosa is a major multidrug-resistant pathogen whose biofilm formation complicates treatment. Rugose small colony variants (RSCVs) exhibit enhanced biofilm production and resistance, posing significant clinical challenges; however, their formation mechanisms in clinical strains remain incomplet...

Qing Yu, Yue Li, Pei-Qi Wang et al. · Microbiology spectrum · 0 citations