Curcumin inhibits atherosclerotic plaque formation by regulating PLCG2 ubiquitination in vascular smooth muscle cells.
Atherosclerosis (AS) is a chronic inflammatory disease in which vascular smooth muscle cell (VSMC) pyroptosis and foam cell formation play critical roles. Curcumin has anti-atherosclerotic effects, but its molecular mechanism remains unclear. In this study, we investigated whether and how curcumin regulates VSMC pyropt...