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Review Open access Sep 2026

Immunometabolic Regulation of Macrophage Function in Cardio-Hepatic-Renal Comorbidities: Mechanisms and Therapeutic Opportunities.

This review examines metabolic comorbidities affecting the heart, liver and kidney. The clinical prevalence of cardiohepatorenal metabolic comorbidities associated with obesity and type 2 diabetes is substantial. Chronic low-grade inflammation serves as the fundamental pathogenic mechanism. Abnormal macrophage activati...

Xiao-Fan Bai, Jiang Bai, Yun Zhou · 0 citations

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