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Yunfeng Hu

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Sep 2026

Oxymatrine suppresses stiffness-induced epithelial-mesenchymal transition in breast cancer by targeting the PKN3-GRAF1 signaling axis.

PURPOSE Increased extracellular matrix stiffness is a critical driver of epithelial-mesenchymal transition (EMT) and metastatic progression in breast cancer; however, effective pharmacological strategies targeting intracellular mechanotransduction remain limited. This study investigated whether oxymatrine, a bioactive...

Yunfeng Hu, Xiang Wu, Xi-Yu Xiong et al. · 0 citations

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