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Open access Sep 2026

Paeoniflorin restores redox homeostasis in oxidatively challenged C2C12 myoblasts via activation of the Nrf2/HO-1 pathway

Results support a potential role for paeoniflorin in maintaining muscle cell homeostasis under oxidative stress and indicate that paeoniflorin enhances resistance to oxidative stress in myoblasts through Nrf2/HO-1 pathway activation, thereby preserving genomic stability and mitochondrial function.

Cheol Park, E. Bang, Chengrong Jin et al. · 0 citations
Jul 2026

Luteolin reverses chemoresistance in colorectal cancer cells via TET1/TDG-dependent epigenetic repression of β-catenin.

It is demonstrated that luteolin reverses chemoresistance by suppressing the TET1/TDG-β-catenin axis through epigenetic regulation and modulation of intracellular redox homeostasis, supporting its potential as an adjuvant for CRC chemotherapy.

K. Kang, Mei-Jing Piao, H. Senavirathna et al. · 0 citations

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