Open access
Jul 2026
Integrating network pharmacology, molecular docking, and experimental validation to investigate the therapeutic effects and potential mechanisms of lycopene against pancreatic ductal adenocarcinoma
Preliminary mechanistic evidence is provided for further preclinical investigation of lycopene in PDAC, but its translational application will require optimized formulations, pharmacokinetic validation, and in vivo efficacy studies to overcome its limited bioavailability.
Shaoyang Huang, Dandan Gu, Dan Song et al.
· Frontiers in Nutrition · 0 citations