Open access
Sep 2026
A Green Chemoenzymatic Route to 28-epi-Homobrassinolide Enabled by OsO4-Free Strategy and Engineered Baeyer-Villiger Monooxygenase With MOF Immobilization.
28-epi-homobrassinolide (28-epi-HBL), a bioactive analog of the steroidal phytohormone brassinolide, exhibits broad biological activities and considerable application potential. However, conventional chemical routes remain limited by tetrahydroxylation step that relies on highly toxic osmium tetroxide in combination wi...
Chuan-Yu Fu, Ruoyu Jiao, Yunyijie Zhou et al.
· Biotechnology and Bioenginee... · 0 citations